Modern thought begins in doubt. René Descartes decided to doubt everything, even his own existence, before he hit bedrock: If doubting is going on, there must be a doubter. So there is something real, i.e. the doubter. I think, therefore I am. Boom! He had found a sure foundation. And build upon it he did. He was a mathematical genius who anticipated most STEM fields today. Descartes is a symbolic launch-point for modern science and technology, a forerunner of the digital age.
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